Etiology of OHSS and use of dopamine agonists

A review of the role played by VEGF on OHSS etiologyand the protective effect of dopamine agonists.

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Sérgio Reis Soares, Ph.D., M.D.

Vol 97, Issue 3, Pages 517-522


Vascular endothelial growth factor is the factor that causes increased capillary permeability and therefore the most serious manifestations of ovarian hyperstimulation syndrome. Dopamine agonists can both prevent and treat ovarian hyperstimulation syndrome by blocking expression of the vascular endothelial growth factor receptor.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.