Increased maternal cardiovascular mortality associated with pregnancy in women with Turner syndrome

This revised Committee Opinion outlines reproductive issues relevant to women with Turner syndrome, including associated maternal morbidity and mortality, oocyte donation, prenatal testing and care, and alternatives to infertility treatment, such as surrogacy or adoption.

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Practice Committee of the American Society for Reproductive Medicine

Volume 97, Issue 2 , Pages 282-284


In women with Turner syndrome, the risk of death from aortic dissection or rupture during pregnancy may be 2%, and this risk persists during the postpartum period owing to pregnancy-related aortic changes. Turner syndrome is a relative contraindication for pregnancy; however, it is an absolute contraindication for pregnancy in a patient with a documented cardiac anomaly. This document replaces the 2008 document of the same name.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility┬« is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.