Does PCOS have developmental origins?

The pros and cons of the proposition that PCOS has developmental origins are laid out based on the best available evidence.

0
0
Like 0 Comment

Author

Stephen Franks, M.D., F.Med.Sci. and Sarah L. Berga, M.D.

Volume 97, Issue 1 , Pages 2-6

Abstract

PRO—The similarity of reproductive and metabolic phenotype between prenatally androgenized sheep, or monkeys, and women with PCOS provides strong supportive evidence for developmental programming being important in the etiology of PCOS. CON—While one would not exclude altogether developmental determinants of PCOS, it is difficult to view PCOS as purely developmental or resulting only from intrauterine exposures or simply an adaptation gone astray.

Read the full text at: http://www.fertstert.org/article/S0015-0282(11)02805-6/fulltext

Go to the profile of Fertility and Sterility

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

No comments yet.