Term oocyte maturation and term ovarian stimulation: impact on oocyte competence


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VOLUME 114, ISSUE 2, P221-222


Dmitri I. Dozortsev, M.D., Ph.D., Antonio Pellicer, M.D., Michael P. Diamond, M.D.


A recent study has clearly demonstrated that the rate of chromosomal errors is the same whether the embryo achieved the blastocyst stage in vitro or in vivo. One of the important conclusions that can be drawn from this study is the overwhelming impact of ovarian stimulation on the egg quality, as opposed to subsequent steps, including fertilization and culture. This makes optimization of ovarian stimulation protocols ever more important, as evidently this is the only instrument in the arsenal of assisted reproduction technology to improve the quality of the egg.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.