Human female meiosis checkpoints: how much DNA damage is allowed?

Reflections
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Editorial Office, American Society for Reproductive Medicine
Human female meiosis checkpoints: how much DNA damage is allowed?
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Human female meiosis checkpoints: how much DNA damage is allowed?

The process of oocyte maturation is complex, consisting of sequential events taking place in the cytoplasm and the nucleus of the cell. A mature “competent” oocyte is able to undergo fertilization, reinitiate and complete meiosis, and support the embryo through its first few cellular divisions, unti…

Volume 113, Issue 5, Pages 943–944

Authors:

Elpida Fragouli, Ph.D., F.R.S.B., F.I.B.M.S., Nicolas Garrido, Ph.D.

Abstract:

Reflections on "Human oocytes harboring damaged DNA can complete meiosis I" by Gaudeline Rémillard-Labrosse et al.


Read the full text here.

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Fertility and Sterility
Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. 

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