Frozen embryo transfer: evidence-based markers for successful endometrial preparation

Only about one-half of euploid embryos result in a live birth when in frozen-thawed embryo transfer cycles. Endometrial or other factors are equal in importance to chromosomal number in determining birth outcome.

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Volume 113, Issue 2, Pages 248–251


Robert F. Casper, M.D., F.R.C.S.(C.)


Endometrial receptivity appears to be as important as chromosomal normality in determining embryo implantation and pregnancy outcome, because the ongoing pregnancy rate with transfer of preimplantation genetic testing for aneuploidy euploid blastocysts is ∼50%. This Views and Reviews article focuses on our current knowledge of the biology of endometrial receptivity and on the role of both invasive (endometrial biopsy) and noninvasive (ultrasound) assessment in successful endometrial preparation for frozen-thawed embryo transfer.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. 


Go to the profile of Patricia Perfumo
over 1 year ago

I  listened to Dr Casper in Sevilla and  was very impressed with  his lecture .  I want to  get in touch with him to reproduce the  research in my center. 

I think it Is a useful tool to improve the results of IVF.