Selecting the most competent sperm for assisted reproductive technologies

We provide an overview of effective methods used to select competent sperm for ART, with case-specific guidance for choosing the best method in common clinical scenarios.

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Volume 111, Issue 5, Pages 851–863


Rajasingam S. Jeyendran, B.V.Sc., M.S., Ph.D., Ettore Caroppo, M.D., Alexandre Rouen, M.D., Ph.D., Anthony Anderson, D.H.Sc., Elizabeth Puscheck, M.D., M.S., M.B.A.


This paper discusses the variety of effective sperm selection techniques that have been developed for use in assisted reproductive technologies. Available methods for isolating the competent sperm in an ejaculate are outlined, as well as techniques for selecting single sperm for use in intracytoplasmic sperm injection procedures. Case-specific methods for selecting the most competent sperm are discussed, with reference to the potential causes of male factor infertility and guidance for the embryologist based on the issues present for each couple seeking treatment.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.