Fertility and Sterility

Targeting the transforming growth factor-β pathway: a novel mechanism of ulipristal acetate action against uterine fibroids

Uterine fibroids are benign monoclonal neoplasms of the myometrium that represent the most common tumor in reproductive-age women worldwide. Their prevalence is approximately 70%–80% in women by the age of 50 years. Histopathology analysis shows increased smooth muscle cells, collagen, proteoglycans…