Volume 111, Issue 2, Pages 229–238
Authors:
Antonio Capalbo, Ph.D., Davit Chokoshvili, Ph.D., Lorraine Dugoff, M.D., Jason Franasiak, M.D., Norbert Gleicher, M.D., Guido Pennings, Ph.D., Carlos Simon, M.D., Ph.D.
Abstract:
PRO: The reproductive risk of a couple aiming to conceive should be tested in the contemporary clinical context
CON: The reproductive risk of a couple aiming to conceive should not be tested in the contemporary clinical context
Should we stop offering endometrial scratching prior to in vitro fertilization?
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It is certainly important to offer, as part of medically assisted reproduction, carrier screening before ART. However, it seems to me essential to frame this approach (consensus) to avoid to drift towards an eugenicist approach and to widen the gap between the status of the child born naturally and that born by IVF. PGT is already widely used for fertile couples who want to choose the sex of their child, which is ethically very controversial. What is the risk of drift with these genetic tests?
While both sides make excellent points in this "fertile battle", my vote is for "yes", the reproductive risk of a couple aiming to conceive should be tested in the contemporary clinical context.
Well-counseled patients should have the choice of whether or not to undergo carrier testing (and what panel), with an ongoing evaluation of what panels should be offered. Genetic counselors will play an increasingly important role in the practice of ART.