Genetics of primary ovarian insufficiency: a careful step-by-step approach based on solid foundations to bring new knowledge

Letter to the Editor
Published
Go to the profile of Fertility and Sterility
Fertility and Sterility
Editorial Office, American Society for Reproductive Medicine
Like

Related Content

Fertility and Sterility
Fertility and Sterility Fertility and Sterility

Genetics of primary ovarian insufficiency: a careful step-by-step approach based on solid foundations to bring new knowledge

Primary ovarian insufficiency (POI) affects 1% of women ≤40 years of age (1). Next-generation sequencing, especially whole-exome sequencing (WES), has recently unraveled many novel genetic causes (1).

VOLUME 118, ISSUE 2, P421-424

Authors:

Abdelkader Heddar, M.D., Micheline Misrahi, M.D., Ph.D.

Abstract:

Primary ovarian insufficiency (POI) affects 1% of women ≤40 years of age (1). Next-generation sequencing, especially whole-exome sequencing (WES), has recently unraveled many novel genetic causes (1).
Very recently, Rouen et al. (2) used WES in 36 familial cases of POI and report a positive diagnostic yield of 50% in this issue of Fertility and Sterility.

Read the full text here. 

Go to the profile of Fertility and Sterility
Fertility and Sterility
Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. 

Please sign in or register for FREE

Your Fertility and Sterility Dialog login information is not the same as your ASRM or EES credentials. Users must create a separate account to comment or interact on the Dialog.

Sign In Register

Recommended Content