The efficacy of different treatments for type 2 cesarean scar pregnancy

Ultrasound-guided injection of lauromacrogol with vacuum aspiration is recommended for patients with type 2 cesarean scar pregnancy <49 days of gestation, whereas laparotomy/laparoscopy with hysteroscopy for those >49 days.
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VOLUME 118, ISSUE 2, P407-413

Authors:

Wei Zhou, M.B., Xingjun Feng, M.B., Jiazheng Yu, M.B., Zeying Chai, M.M., Lingzhi Zheng, M.B., Feng Qi, M.M. 

Abstract:

Objective

To study the efficacy of 3 treatment options for type 2 cesarean scar pregnancy (CSP) and establish an optimal treatment strategy for type 2 CSP.


Design

Retrospective cohort study.


Setting

A tertiary hospital.


Patients

The study examined 160 women with type 2 CSP.


Interventions

Ultrasound-guided vacuum aspiration after local injection of lauromacrogol, ultrasound-guided vacuum aspiration after uterine artery embolization (UAE), and transabdominal resection or hysteroscopy combined with laparoscopic resection.


Main outcome measures

The success rates, duration of hospitalization, hospitalization cost, amount of blood loss, recovery time, and menstruation resuming after recovery.


Results

The success rates of the UAE, lauromacrogol, and surgical groups were 87.1%, 92.5%, and 95.5%, respectively, with no significant differences. The cost and duration of hospitalization in the lauromacrogol group were significantly lower than those in the UAE and surgical groups. Analysis of the causes of treatment failure revealed a significant difference in the gestational age. The area under the receiver operating characteristic curve was 0.660 (95% confidence interval, 0.533–0.788). When the gestational age was 48.5 days, Youden index was the highest. Furthermore, when the diagnostic thresholds were selected as 49, 56, and 63 days of pregnancy, the corresponding areas under the receiver operating characteristic curve were 0.652, 0.541, and 0.510, respectively.


Conclusion

Ultrasound-guided vacuum aspiration after local injection of lauromacrogol is recommended for patients with type 2 CSP at <49 days of gestation. Laparotomy or laparoscopy combined with hysteroscopy is suitable for patients with gestation of >49 days, especially for those with >56 days of gestation.

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