Oligo-anovulation is not a rarer feature in women with documented endometriosis

Oligo-anovulation is not an infrequent feature in women with documented endometriosis.

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Fertility and Sterility
Editorial Office, American Society for Reproductive Medicine
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Volume 110, Issue 5, Pages 941–948

Authors:

Pietro Santulli, M.D., Ph.D., Chloe Tran, M.D., Vanessa Gayet, M.D., Mathilde Bourdon, M.D., Chloe Maignien, M.D., Louis Marcellin, M.D., Khaled Pocate-Cheriet, M.D., Charles Chapron, M.D., Dominique de Ziegler, M.D.

Abstract:

Objective

To study the prevalence of oligo-anovulation in women suffering from endometriosis compared to that of women without endometriosis.

Design

A single-center, cross-sectional study.

Setting

University hospital-based research center.

Patient (s)

We included 354 women with histologically proven endometriosis and 474 women in whom endometriosis was surgically ruled out between 2004 and 2016.

Intervention

None.

Main Outcome Measure(s)

Frequency of oligo-anovulation in women with endometriosis as compared to that prevailing in the disease-free reference group.

Results

There was no difference in the rate of oligo-anovulation between women with endometriosis (15.0%) and the reference group (11.2%). Regarding the endometriosis phenotype, oligo-anovulation was reported in 12 (18.2%) superficial peritoneal endometriosis, 12 (10.6%) ovarian endometrioma, and 29 (16.6%) deep infiltrating endometriosis.

Conclusion(s)

Endometriosis should not be discounted in women presenting with oligo-anovulation.


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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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