A review of best practices of rapid-cooling vitrification for oocytes and embryos: a committee opinion

This committee opinion reviews background of vitrification, defines terminology, and determines best practices for rapid-cooling vitrification of oocytes and embryos.

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VOLUME 115, ISSUE 2, P305-310


Practice Committees of the American Society for Reproductive Medicine and Society of Reproductive Biologists and Technologists 


The focus of this paper is to review best practices for rapid-cooling cryopreservation of oocytes and embryos. The discussion of best practices includes the types of cryoprotectants and cryo devices typically used. Key performance indicators of rapid-cooling vitrification success are defined.

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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