Comparison of pregnancy rates for poor responders using IVF with mild ovarian stimulation versus conventional IVF: a guideline

In patients classified as poor responders, in vitro fertilization (IVF) with mild ovarian stimulation appears to result in similarly low pregnancy rates comparable to IVF with conventional stimulation.

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Volume 109, Issue 6, Pages 993–999


Practice Committee of the American Society for Reproductive Medicine


Mild-stimulation protocols with in vitro fertilization (IVF) generally aim to use less medication than conventional IVF. This guideline evaluates pregnancy and live-birth rates in patients expected to be poor responders using mild ovarian stimulation and natural-cycle protocols vs conventional IVF.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.