Comparison of pregnancy rates for poor responders using IVF with mild ovarian stimulation versus conventional IVF: a guideline

In patients classified as poor responders, in vitro fertilization (IVF) with mild ovarian stimulation appears to result in similarly low pregnancy rates comparable to IVF with conventional stimulation.

Volume 109, Issue 6, Pages 993–999


Practice Committee of the American Society for Reproductive Medicine


Mild-stimulation protocols with in vitro fertilization (IVF) generally aim to use less medication than conventional IVF. This guideline evaluates pregnancy and live-birth rates in patients expected to be poor responders using mild ovarian stimulation and natural-cycle protocols vs conventional IVF.

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