Fertility and Sterility

HMGA2 involvement in uterine leiomyomas development through angiogenesis activation

Uterine leiomyoma (UL) is the most common benign estrogen-dependent tumor in women of reproductive age, affecting 25% of women and has a cumulative incidence of 70% in women by the age of 50 years because leiomyomas can be present without symptoms in most of them (1). However, 15% to 30% of women wi…