Time-lapse imaging: clearly useful to both laboratory personnel and patient outcomes versus just because we can doesn't mean we should
Volume 109, Issue 4, Pages 584–591
Richard J. Paulson, M.D., M.S., David E. Reichman, M.D., Nikica Zaninovic, M.S., Ph.D., H.C.L.D., E.L.D., Linnea R. Goodman, M.D., Catherine Racowsky, Ph.D.
Over the last 50 years, embryo culture techniques for in vitro fertilization (IVF) have continued to evolve. The latest evolution raises a controversial question—whether culturing embryos in systems which allow for undisturbed time-lapse monitoring (TLM) improve our fundamental understanding of embryogenesis, and whether that understanding can reliably translate into improved clinical outcomes (1).