Association between use of marijuana and time to pregnancy in men and women: findings from the National Survey of Family Growth
Using a nationally representative population-based sample, marijuana use was not associated with time to pregnancy for both men and women.
Volume 109, Issue 5, Pages 866–871
Alex M. Kasman, M.D., Marie E. Thoma, Ph.D., Alexander C. McLain, Ph.D., Michael L. Eisenberg, M.D.
To determine if regular use of marijuana has an impact on time to pregnancy.
Retrospective review of cross-sectional survey data from male and female respondents aged 15–44 years who participated in the 2002, 2006–2010, and 2011–2015 National Survey of Family Growth.
The National Survey of Family Growth is a nationally representative population-based sample derived from stratified multistage area probability sampling of 121 geographic areas in the U.S. Our analytic sample was participants who were actively trying to conceive.
Exposure status was based on the respondents' answers regarding their marijuana use in the preceding 12 months.
Main Outcome Measure(s)
The main outcome was estimated time to pregnancy, which was hypothesized before analysis to be delayed by regular marijuana use.
A total of 758 male and 1,076 female participants responded that they were actively trying to conceive. Overall, 16.5% of men reported using any marijuana while attempting to conceive, versus 11.5% of women. The time ratio to pregnancy for never smokers versus daily users of marijuana in men was 1.08 (95% confidence interval 0.79–1.47) and in women 0.92 (0.43–1.95), demonstrating no statistically significant impact of marijuana use on time to pregnancy.
Our study suggests that neither marijuana use nor frequency of marijuana use was associated with time to pregnancy for men and women.