The use of preimplantation genetic testing for aneuploidy (PGT-A): a committee opinion
Use of preimplantation genetic testing for aneuploidy (PGT-A) in select patients undergoing in vitro fertilization has been theorized to allow for higher live-birth rates when increased elective single-embryo transfer is used. PGT-A testing reliability has recently come under scrutiny. The impact of mosaicism on testing re- liability and embryo damage from the biopsy still need to be determined.
Volume 109, Issue 3, Pages 429–436
Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology
The value of preimplantation genetic testing for aneuploidy (PGT-A) as a screening test for in vitro fertilization (IVF) patients has yet to be determined. Several studies demonstrate higher birth rates after aneuploidy testing and elective single-embryo transfer (eSET), suggesting the potential for this testing to decrease the risk of multiple gestations, though these studies have important limitations.