In vitro fertilization twins: acceptable when desired, or iatrogenic complication preventable through elective single embryo transfer?

Fertile Battle

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Volume 109, Issue 2, Pages 221–222


David R. Meldrum, M.D.


An obstetrician recently shared her emotionally draining experience managing live delivery of in vitro fertilization (IVF) twins at 20 weeks gestation (1). Over my 35 years in IVF I have heard of many pre-viable losses of IVF twins. Her wrenching account should be required reading for any IVF provider who allows transfer of two embryos outside of Society for Assisted Reproductive Technology (SART) guidelines.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.