Sclerotherapy in the management of ovarian endometrioma: Systematic review and meta-analysis.

Sclerotherapy should be considered for the manage- ment of ovarian endometrioma in symptomatic women who plan to conceive.

Like Comment

Volume 108, Issue 1, Pages 117–124.e5

Authors:

Aviad Cohen, M.D., Benny Almog, M.D., Togas Tulandi, M.D., M.H.C.M.

Abstract:

Objective

To evaluate the efficacy of sclerotherapy for ovarian endometrioma on the risk of recurrence, clinical symptoms, and reproductive function.

Design

Systematic review and meta-analysis.

Setting

Not applicable.

Patient(s)

Patients who underwent sclerotherapy of ovarian endometrioma.

Intervention(s)

An electronic-based search with the use of Pubmed, Embase, Ovid Medline, Google Scholar, Clinicaltrials.gov, and the Cochrane Central Register of Controlled Trials.

Main Outcome Measure(s)

Recurrence rate, symptoms relief, fertility outcome, and adverse events.

Result(s)

Eighteen studies were included in our review. The overall recurrence rates of endometrioma after sclerotherapy ranged from 0 to 62.5%. The risk of recurrence was significantly higher in women who were treated by means of ethanol washing than by means of ethanol retention. The number of oocytes retrieved was higher after endometrioma sclerotherapy compared with laparoscopic cystectomy, but clinical pregnancy rates were similar. There was no difference in the number of oocytes retrieved and the clinical pregnancy rates between the sclerotherapy-treated group with and the untreated group.

Conclusion(s)

Sclerotherapy for ovarian endometrioma may be considered in symptomatic women who plan to conceive.


Read the full text here.



Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

No comments yet.