In vitro fertilization with preimplantation genetic diagnosis for aneuploidies in advanced maternal age: a randomized, controlled study

Preimplantation genetic diagnosis for aneuploidies is superior to blastocyst transfer, not only in clinical outcome at first embryo transfer but also in dramatically decreasing miscarriage rates and shortening time to pregnancy.

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Volume 107, Issue 5, Pages 1122–1129


Carmen Rubio, Ph.D., José Bellver, M.D., Lorena Rodrigo, Ph.D., Gema Castillón, M.D., Alfredo Guillén, M.D., Carmina Vidal, M.D., Juan Giles, M.D., Marcos Ferrando, M.D., Sergio Cabanillas, M.D., José Remohí, M.D., Ph.D., Antonio Pellicer, M.D., Ph.D., Carlos Simón, M.D., Ph.D.


Preimplantation genetic diagnosis for aneuploidy screening is superior compared with controls not only in clinical outcome at the first ET but also in dramatically decreasing miscarriage rates and shortening the time to pregnancy.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.