The most well kept secret, embryo culture media: a smart reveal from an expert
Volume 107, Issue 4, Page 910
Marcos Meseguer, Ph.D., Antonio Pellicer, M.D.
The introduction of in vitro fertilization (IVF) treatments was only possible when all those investigations that took place in tissue culture were adapted for human embryos. But human embryo culture is very different from other cell culture, because somatic cells are surrounded by the extracellular fluid rich in nutrients whereas embryos are simply bounded by a very low amount of uterine fluid that reflects location and chronologic changes (1). Since the beginning of assisted reproductive technology (ART) in the 1980s, media conception, configuration, and composition may have changed dramatically, and we may consider that a portion of the improved success in IVF programs came along with enhanced formulations and detailed user protocols (2).