Obesity, male infertility, and the sperm epigenome

In men of reproductive age, obesity negatively affects fertility through changes in androgen processing and epigenetic changes in the male genome and sperm genome. These changes may also the progeny of affected men.

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Volume 107, Issue 4, Pages 848–859

Authors:

James R. Craig, M.D., Timothy G. Jenkins, Ph.D., Douglas T. Carrell, Ph.D., H.C.L.D., James M. Hotaling, M.D., M.S., F.E.C.S.M.

Abstract:

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

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