Perinatal outcomes among singletons after assisted reproductive technology with single-embryo or double-embryo transfer versus no assisted reproductive technology

Compared to non-assisted reproductive singletons, single-embryo transfer singletons did not have increased odds of adverse perinatal outcomes. Double- embryo transfer singletons with 2 early fetal heartbeats estabished had the highest odds.

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Volume 107, Issue 4, Pages 954–960


Angela S. Martin, M.D., Jeani Chang, M.P.H., Yujia Zhang, Ph.D., Jennifer F. Kawwass, M.D., Sheree L. Boulet, Dr.P.H., Patricia McKane, D.V.M., Dana Bernson, M.P.H., Dmitry M. Kissin, M.D., Denise J. Jamieson, M.D. for the States Monitoring Assisted Reproductive Technology (SMART) Collaborative


Compared with non-ART singletons, singletons born after eSET and non-eSET did not have increased risks whereas DET −1 and DET ≥2 singletons were more likely to have adverse perinatal outcomes.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.