Partial suppression of estradiol: a new strategy in endometriosis management?


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Volume 107, Issue 3, Pages 568–570


Jacques Donnez, M.D., Ph.D., Robert N. Taylor, M.D., Ph.D., Hugh S. Taylor, M.D.


Endometriosis is a chronic inflammatory disease responsible for pelvic pain and infertility (1) and characterized by frequent recurrence of symptoms and lesions, even after surgery (2). There is a lack of data from randomized clinical trials on the optimal management of endometriosis (medical versus surgical) in terms of pain relief and recurrence (2). Surgery is indicated unquestionably in cases of endometriomas more than 3 to 4 cm, as well as deep nodular endometriosis, particularly when associated with infertility. However, recurrence is common and everything must be done to prevent it.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders.