Volume 107, Issue 2, Pages 334–335
Jacques Donnez, M.D., Ph.D., Olivier Donnez, M.D., Ph.D., Marie-Madeleine Dolmans, M.D., Ph.D.
Uterine fibroids, the most frequently encountered benign uterine tumors, have a profound impact on the quality of life (QOL) of patients. Moreover, they are associated with a considerable societal burden due to the direct costs of treatment and the indirect costs linked to work absenteeism. Around 30% of women with leiomyomas will request treatment because of severe heavy menstrual bleeding, abdominal pain, bulk symptoms, and/or infertility.