Vitamin D in human reproduction—an evolving landscape


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Volume 106, Issue 7, Pages 1650-1651


Jason M. Franasiak, M.D., T.S. (A.B.B.)


Reflections on "Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and anti-Mullerian hormone production" by Xu et al.

Read the full text here.

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.


Go to the profile of Alexander Quaas
Alexander Quaas almost 4 years ago

Jason- these are interesting reflections on an exciting topic. I am sure our understanding of the relationship between Vitamin D and reproduction will evolve further in the next months and years. Do you currently check Vitamin D levels routinely on all (new) patients?

Go to the profile of Evelin Lara-Molina
Evelin Lara-Molina over 3 years ago

Thank you Jason for this original and insightful article! Hopefully, our knowledge about this interesting issue will evolve progressively.

Go to the profile of Jason Franasiak
Jason Franasiak over 3 years ago

Thanks to both Drs. Molina and Quaas for their comments. The vitamin D deficiency epidemic in the US is certainly complex given challenges with measurements and definitions. At present, given easy assessment (blood draw) and easy treatment (over the counter supplementation or more time at the beach) I do assess Vitamin D with new patient intake. There is some evidence to show that this may be impactful on reproduction (from the oocyte or the uterus, perhaps less clear) and I think the harm of intervention is very minimal with standard oral supplementation.