Criteria, prevalence, and phenotypes of polycystic ovary syndrome

The authors review the evolution of the criteria used to diagnosis polycystic ovary syndrome, the prevalence of the disorder, the distribution of polycystic ovary syndrome phenotypes, their morbidity, and the role that referral bias plays in the epidemiology of this syndrome.

Like Comment

Authors

Daria Lizneva, M.D., Ph.D, Larisa Suturina, M.D., Ph.D., Walidah Walker, M.P.H., Soumia Brakta, M.D., Larisa Gavrilova-Jordan, M.D., Ricardo Azziz, M.D., M.P.H., M.B.A.

Abstract

Polycystic ovary syndrome (PCOS) is a highly prevalent disorder effecting reproductive-aged women worldwide. This article addresses the evolution of the criteria used to diagnosis PCOS; reviews recent advances in the phenotypic approach, specifically in the context of the extended Rotterdam criteria; discusses limitations of the current criteria used to diagnosis, particularly when studying adolescents and women in the peri- and postmenopause; and describes significant strides made in understanding the epidemiology of PCOS. This review recognizes that although there is a high prevalence of PCOS, there is increased variability when using Rotterdam 2003 criteria, owing to limitations in population sampling and approaches used to define PCOS phenotypes. Last, we discuss the distribution of PCOS phenotypes, their morbidity, and the role that referral bias plays in the epidemiology of this syndrome.

Read the full text at: http://www.fertstert.org/article/S0015-0282(16)61232-3/fulltext

Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.

No comments yet.