The preimplantation genetic testing debate continues: first the hype, then the tension, now the hypertension?



Volume 112, Issue 2, Pages 233–234


George Patounakis, M.D., Ph.D.a,b, Micah J. Hill, D.O.c


Reflections on "Maternal and neonatal outcomes associated with trophectoderm biopsy" by Zhang et al.

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Fertility and Sterility

Editorial Office, American Society for Reproductive Medicine

Fertility and Sterility® is an international journal for obstetricians, gynecologists, reproductive endocrinologists, urologists, basic scientists and others who treat and investigate problems of infertility and human reproductive disorders. The journal publishes juried original scientific articles in clinical and laboratory research relevant to reproductive endocrinology, urology, andrology, physiology, immunology, genetics, contraception, and menopause. Fertility and Sterility® encourages and supports meaningful basic and clinical research, and facilitates and promotes excellence in professional education, in the field of reproductive medicine.


Go to the profile of Lisa Papapoliti
Lisa Papapoliti 6 months ago

Despite the methodological flaws that you describe in your critique of the paper, it’s still interesting why a case like mine, with no infertility factor, having had PGD after trophectoderm biopsy for a monogenic disorder, I developed HELLP without any other risk factor for preeclampsia.

Go to the profile of Micah J Hill
Micah J Hill 6 months ago

Thank you for your comment!  We agree that this study justifies further investigation to see if an association exists between PGT and preeclampsia.

Go to the profile of Marine Poulain
Marine Poulain 6 months ago

Further studies are clearly needed bit this is an important question and very few studies on this topic investigate outcomes after clinical pregnancy confirmation. I’m looking forward further data!