April 2016

All the papers from the April 2016 issue of Fertility and Sterility.

Dysregulated leukemia inhibitory factor and its receptor regulated signal transducers and activators of transcription 3 pathway: a possible cause for repeated implantation failure in women with dormant genital tuberculosis

Poor expression of implantation markers and altered leukemia inhibitory factor–signal transducers and activators of transcription 3 (LIF-STAT3) signaling in women with dormant genital tuberculosis is associated with implantation failure. Alterations in LIF-STAT3 signaling in heat shock protein-65-treated human endometrial stromal cells confirms compromised endometrial decidualization.

Role for male reconstruction in the era of assisted reproductive technology

Microsurgical reconstruction for male infertility is a relatively recent development in the history of urology therapy. The results of the first microsurgical vasovasostomy (VV) were published in the late1960s, and this epic achievement has been followed by almost fifty years of microsurgical innovation (1). Despite the well-established success of microsurgery, the role of male reproductive tract reconstruction has been called into question because of the many advances made in assisted reproductive technology (ART).

Reconstructive tubal microsurgery and assisted reproductive technology

For the infertile woman with tubal damage, there are only two realistic options for achieving a pregnancy: reconstructive surgery or in vitro fertilization (IVF). Until the 1980s, reconstructive surgery was the only therapeutic option for infertility caused by tubal and peritoneal factors. Traditional techniques yielded poor outcomes, often as a result of extensive postoperative adhesions. This led to the development of gynecologic microsurgery in the early 1970s. In addition to the use of magnification, microsurgery introduced a broad concept of surgery designed to be more precise, to minimize trauma and tissue damage, and to avoid an acute inflammatory reaction in the peritoneal cavity to obtain better results and prevent postoperative adhesions.

Curbside consultations in the era of social media connectivity and the creation of the SREI Forum

Social media, as defined by Wikipedia, the social encyclopedia, is a computer-mediated tool that allows people to create, share, or exchange information, career interests, ideas, and pictures/videos in virtual communities and networks. A Google search for the term yields 1.2 billion hits and you are hard pressed to get through your morning coffee without being asked to give or receive information through one of the many outlets that fall under this umbrella.