February 2012

All the papers from the February 2012 issue of Fertility and Sterility.

Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes

Plasminogen is present in the oviductal fluid. Plasminogen and plasminogen activators are present in oolemma and zona pellucida of matured oocytes. After IVF, the immunoreactivity for plasminogen and its activators in oocytes decreases. Presence of plasminogen in the IVF medium decreases polyspermy rates.