We describe the early steps that brought about the establishment of assisted fertilization techniques culminating in intracytoplasmic sperm injection (ICSI) along with presentations of current diagnostic screening methods for spermatozoal (dys)function.
This revised Committee Opinion outlines reproductive issues relevant to women with Turner syndrome, including associated maternal morbidity and mortality, oocyte donation, prenatal testing and care, and alternatives to infertility treatment, such as surrogacy or adoption.
Genome-wide sperm DNA methylation patterns were evaluated in abnormal protamine 1/protamine 2 ratio, abnormal IVF/intracytoplasmic sperm injection embryogenesis, and normozoospermic, fertile control men. Broadly aberrant methylation was observed in three patients.
We present a case of variant primary ciliary dyskinesia with complete asthenozoospermia and reduced respiratory function. Testicular sperm extraction was used to retrieve improved-quality sperm, and a healthy child was achieved with the use of intracytoplasmic sperm injection.
In this meta-analysis, infants conceived after elective single embryo transfer have decreased risks of low birth weight and prematurity than after double embryo transfer but higher risks of prematurity than spontaneous conceptions.
Individual human embryos with the potential to develop to high-scoring blastocysts could be selected at 2–3 days of culture using this system by examining the times required to complete the second and third mitotic divisions.
Fragmented oocytes occur rarely in intracytoplasmic sperm injection cycles, but their presence is associated with reduced developmental potential of sibling oocytes and lower implantation and pregnancy rates.
We investigated patients with unexplained recurrent pregnancy loss for expression of antitrophoblast antibodies using choriocarcinoma cell line JEG-3 because these cells retain many characteristics of normal pregnancy-derived trophoblasts.
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