All the papers from the March 2012 issue of Fertility and Sterility.
Agonist trigger: what is the best approach? Agonist trigger with vitrification of oocytes or embryos
Agonist triggering combined with oocyte vitrification and ET in a subsequent natural cycle avoids ovarian hyperstimulation syndrome in patients at risk and shows excellent cycle outcome.
Low-dose hCG supplementation after GnRHa trigger secures the reproductive outcome and minimizes the risk of OHSS in the high-risk IVF patient.
Intensive luteal phase support is effective in improving pregnancy rates after GnRHa trigger.
This Practice Committee guideline provides recommendations regarding the use of surgical procedures for the treatment of tubal disease.
We report on how mild induced testicular and epididymal hyperthermia in men caused drastic and reversible effects on sperm chromatin integrity which appeared before any changes in sperm output.
Nitric oxide synthase and tyrosine nitration in idiopathic asthenozoospermia: an immunohistochemical study
We confirm a pathogenic role of nitric oxide in the reduction of sperm functionality.
A randomized assessor-blind trial comparing highly purified hMG and recombinant FSH in a GnRH antagonist cycle with compulsory single-blastocyst transfer
A randomized, assessor-blind, multicenter trial with compulsory single-blastocyst transfer documented that highly purified hMG is noninferior to rFSH regarding ongoing pregnancy in GnRH antagonist cycles.
The relationship between follicle development and progesterone receptor membrane component-1 expression in women undergoing in vitro fertilization
Eighteen percent of women undergoing IVF overexpressed PGRMC1, which was associated with a 30% reduction in follicle development and the number of mature oocytes but not ongoing pregnancy rates.
Outcomes of singleton births after blastocyst versus nonblastocyst transfer in assisted reproductive technology
Retrospective cohort analysis of 4,202 births resulting from blastocyst versus nonblastocyst transfer demonstrated no significant difference in maternal and perinatal outcomes, although blastocyst transfer may increase preeclampsia and placenta previa.
We report that ovarian hyperstimulation as part of in vitro fertilization led to significant elevations in TSH, often above pregnancy-appropriate targets. These findings were particularly evident in participants with preexisting hypothyroidism.
High expression of luteinizing hormone receptors messenger RNA by human cumulus granulosa cells is in correlation with decreased fertilization
This is the first demonstration that LH receptor expression increases during antral follicular growth, is highest in preovulatory follicles, and correlates with fertility treatment outcome.
Effects of acupuncture on pregnancy rates in women undergoing in vitro fertilization: a systematic review and meta-analysis
We present a systematic review and meta-analysis performed to evaluate the effect of acupuncture on pregnancy rates in women undergoing IVF.
Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study
Pre-emptive use of ibuprofen had a statistically significant beneficial effect on the need for pain relief during a mifepristone and misoprostol regimen for medical abortion. Ibuprofen did not adversely affect the outcome of medical abortion.
A randomized, phase II study describing the efficacy, bleeding profile, and safety of two low-dose levonorgestrel-releasing intrauterine contraceptive systems and Mirena
Two new low-dose LNG-IUSs provided effective contraception with a similar bleeding profile to Mirena and were significantly easier and less painful to place compared with Mirena.
Severe maternal morbidity in ectopic pregnancy is not associated with maternal factors but may be associated with quality of care
We report that severe maternal morbidity from hemorrhage in women with ectopic pregnancy is not associated with patient-related risk factors.
Birth outcomes after spontaneous or assisted conception among infertile Australian women aged 28 to 36 years: a prospective, population-based study
More than 40% of Australian women aged 28 to 36 years with a history of infertility can achieve births without using fertility treatment, indicating they are subfertile rather than infertile.