GnRH antagonist cycles are associated with a lower risk of OHSS and should be the protocol of choice in high-risk patients; and coasting is a useful protocol for prevention of OHSS.
Agonist triggering combined with oocyte vitrification and ET in a subsequent natural cycle avoids ovarian hyperstimulation syndrome in patients at risk and shows excellent cycle outcome.
FSH co-trigger after ovarian stimulation has been shown to improve oocyte competence and a recent report suggested that the FSH co-trigger can completely prevent OHSS.
Dopamine agonists, decreased FSH and hCG doses, coasting, agonist trigger, paracentesis, metformin, low-dose aspirin, anticoagulation, and possibly FSH co-trigger are measures that prevent or reduce the severity of OHSS.
We report on how mild induced testicular and epididymal hyperthermia in men caused drastic and reversible effects on sperm chromatin integrity which appeared before any changes in sperm output.
A randomized, assessor-blind, multicenter trial with compulsory single-blastocyst transfer documented that highly purified hMG is noninferior to rFSH regarding ongoing pregnancy in GnRH antagonist cycles.
Eighteen percent of women undergoing IVF overexpressed PGRMC1, which was associated with a 30% reduction in follicle development and the number of mature oocytes but not ongoing pregnancy rates.
Retrospective cohort analysis of 4,202 births resulting from blastocyst versus nonblastocyst transfer demonstrated no significant difference in maternal and perinatal outcomes, although blastocyst transfer may increase preeclampsia and placenta previa.
We report that ovarian hyperstimulation as part of in vitro fertilization led to significant elevations in TSH, often above pregnancy-appropriate targets. These findings were particularly evident in participants with preexisting hypothyroidism.
This is the first demonstration that LH receptor expression increases during antral follicular growth, is highest in preovulatory follicles, and correlates with fertility treatment outcome.
Pre-emptive use of ibuprofen had a statistically significant beneficial effect on the need for pain relief during a mifepristone and misoprostol regimen for medical abortion. Ibuprofen did not adversely affect the outcome of medical abortion.
Two new low-dose LNG-IUSs provided effective contraception with a similar bleeding profile to Mirena and were significantly easier and less painful to place compared with Mirena.
More than 40% of Australian women aged 28 to 36 years with a history of infertility can achieve births without using fertility treatment, indicating they are subfertile rather than infertile.
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