Presented at the American Association of Gynecologic Laparoscopists 40th Global Congress of Minimally Invasive Gynecology, Hollywood, Florida, November 6-10, 2011.

Presented at the American Society for Reproductive Medicine annual meeting, Denver, Colorado, October 26, 2010.

This report describes the peripheral levels of inhibin B and antimullerian hormone in boys during peripuberty and in patients with congenital hypogonadotropic hypogonadism.

Coadministration of visfatin during superovulation improved ovarian expression of visfatin and vascular endothelial growth factor, developmental competency of oocytes, and fertility in aged female mice.

The in vitro treatment of mouse spermatozoa with anti-ACTL7a antibody-containing serum and the active immunization of mice using purified ACTL7a protein resulted in significant reductions in fertility.

Complete denudation of oocytes before slush nitrogen vitrification does not affect survival rate but is associated with a higher incidence of postthaw meiotic spindle visualization.

Neurokinin B and kisspeptin regulate human female reproductive function by exerting a direct effect on peripheral reproductive tissues.

B4GALNT2 is localized on the surface of E3.5 blastocyst but is an intracellular component in uterine epithelia. The involvement of B4GALNT2 and Sda antigen in embryonic implantation was proved.

Arachidonic acid (AA)–derived prostaglandins are important for reproduction. In this study, AA stimulated the cytosolic phospholipase A2a/cyclooxygenase-2 pathway activation in mouse endometrial stromal cells.

Optical imaging is a particularly powerful technique for studying testicular germ cell transplantation in vivo and in vitro by bioluminescence at the molecular level in the small animal models.

We report on how impairment of reproduction in db mice is not mediated by intraovary intact/defective leptin signaling even in the face of a significantly divergent modulation by gonadotropins.

Initial findings suggest that a moderate concentration of the cryoprotectant dimethyl sulfoxide (DMSO) is superior to a high DMSO concentration for both vitrification and slow freezing.

FSHR variants such as Asn680Ser and Ile160Thr may be cofactors for infertility in women who respond poorly to ovarian stimulation, but low ovarian reserve appears to be the main cause.

We describe a novel heterozygous inactivating mutation of the LH/CG receptor.

Gene microarray analysis allows comparison of gene expression of adhesion and normal peritoneal tissues. We identified several specific genes with functions relevant to the pathogenesis of postoperative adhesions.

Solid-surface vitrification resulted in success rates similar to conventional uncontrolled slow freezing inpreserving the integrity and function of prepubertalmouse testicular tissue.

GST polymorphisms do not increase the risk of endometriosis. A gene–environment interaction was observed for GSTP1Ile/Ile and GSTM1(-/-) and for high/ medium levels of PCB153, PCB180, and total PCBs.

In this prospective cohort study, vigorous PA was associated with reduced fecundability in all women except overweight or obese women. Moderate PA was associated with a small increase in fecundability.

Patients with endometriosis have higher levels of colony-stimulating factor 1 (CSF-1) and its receptor, C-FMS.

It has been suggested an immunologic mechanism is involved in the development of endometriosis. In a genetic association study, we demonstrated a cumulative effect of FOXP3 and FCRL3 polymorphisms in endometriosis.

The pathologic expression of candidate molecules by tubes bearing an ectopic pregnancy does not determine the implantation site, but they may be involved in regulation of the trophoblast.

The use of recombinant LH in patients of advanced reproductive age may improve ART outcomes.

We present oocyte slow-freezing outcomes using a differential sucrose concentration during dehydration (0.2 M) and rehydration (0.3 M).

Management of hydrosalpinges before IVF is usually consistent among SREI/SRS members.

The optimal size of the leading follicle in cycles with clomiphene citrate and letrozole is in the range of 23–28 mm and is closely related to the endometrial thickness.

Laser polar-body biopsy for preimplantation genetic diagnosis in IVF treatment is associated with reduced embryo quality.

A panel of biomarkers that associate with oocyte and pregnancy outcome were identified by use of a metabolomics approach.

Successful testicular sperm extraction was performed with seven vials of sperm frozen for a man with previous right cryptorchidism, pelvic trauma, and left tunica albuginea rupture.

The process of lyophilization has a negative effect on sperm membranes resulting in total loss of motility and viability, but does not alter DNA and sperm head inner structures.

Correlative transcript pairs have suggested their potential use as biomarkers for male fertility. The results show that qPCR may provide a low-cost assay to assess dysplasia of the fibrous sheath.

The combination of EEJ and ICSI gives adequate results for couples with anejaculation due to psychogenic etiology or spinal cord injury. Sperm retrieved by EEJ is characterized by asthenospermia and normal count.

Bacteriospermia and elevated seminal leukocytes (ESL) were common in subfertile men. The presence of ESL, with or without bacteriospermia, was the dominant factor negatively affecting semen parameters in this study.

"A good man is hard to find," Red Sammy said. "Everything is getting terrible. I remember that day you could go off and leave your screen door unlatched. Not no more."

Women feel pressure to conceive later in life, have ongoing misperceptions about assisted reproduction, and are disappointed to discover their dismal chances for a genetic child.

Repeated implantation failure should be assessed for different causes and treated accordingly.

Beyond embryo and endometrium, other known and suspected causes of recurrent IVF failure include obesity, uterine anomalies and fibroids, thyroid disease, tobacco smoke, immune factors, and thrombophilias.

Defective endometrial receptivity is secondary to intrauterine pathology or aberrant development of adhesive properties at the molecular level. Investigation and treatment of endometrial pathology will increase IVF success rates.

Chromosomal abnormalities, sperm DNA damage, zona hardening, inadequate culture conditions, and suboptimal embryo development all play a significant role in the etiology of recurrent implantation failure.

Understanding the mechanisms involved in implantation may improve the outcome of patients with RIF.