Adult stem cells have been identified in human endometrium. Their ability to reconstruct endometrial tissue when transplanted into immunocompromised animals suggests their potential use for treating disorders associated with inadequate endometrium.

We present an overview of gametogenesis from stem cells, with emphasis on generation of human oocytes, future research objectives for this area of work, and potential clinical applications involving human oogonial stem cells.

Three experts in regenerative medicine explore the evidence and expanding future clinical applicability of the human ovarian and endometrial stem cell population, and tissue engineering of reproductive organs and tissues.