Thyroid peroxidase antibody does not have prognostic value regarding the outcome of a subsequent pregnancy, and empirical thyroxine therapy in those who tested positive did not seem to improve outcome.
Trophectoderm morphology, which is significantly related to the rates of ongoing pregnancy and miscarriage, may be the most important parameter when selecting a single blastocyst for transfer.
IVM is an alternative to conventional IVF for women with polycystic ovaries. In vitro maturation avoids the risk of ovarian hyperstimulation syndrome but has a significantly lower live birth rate compared with IVF.
In this retrospective, observational, cohort study with 2,555 women, a rise of serum P levels on the day of hCG administration was associated with a reduced live birth rate after day-5 fresh ET.
Cumulative newborn rates per total number of embryos needed to achieve a newborn provide an accurate idea of the likelihood of success in consecutive ovum donation cycles.
In this research, young women commencing IVF had a subsequent increased rate of breast cancer compared with women seeking infertility treatment at the same age but not requiring IVF.
Sperm cryopreservation increases DNA damage in the cytometric PIbr sperm population, an effect that is partly prevented by extracts of Opuntia ficus-indica and resveratrol.
Polyvinylpyrrolidone-based medium can induce sperm DNA fragmentation during intracytoplasmic sperm injection, and frozen-thawed sperm from oligozoospermic ejaculates are more susceptible to in situ DNA fragmentation.
Human sperm head vacuoles have no effect on intracytoplasmic sperm injection outcomes because they are not abnormal structures but physiological changes occurring during the sperm development and maturation process.
Leading medical societies devoted to the care of menopausal women agree that the decision to initiate hormone therapy should be for the indication of treatment of menopauserelated symptoms.
By effectively preventing OHSS, the antagonist protocol with GnRH-a trigger is a better option for treating women with PCOS than in vitro maturation (IVM).
To date, retrieval of spermatogonial cells in prepubertal boys with Klinefelter syndrome should be viewed as experimental and patients and their parents must be counseled accordingly.
The impact of early hormone therapy on fertility outcomes in patients with Klinefelter syndrome is not well understood. Semen or testicular tissue cryopreservation should be considered in affected adolescents to maximize future fertility potential.
More knowledge about the development of the androgenic and spermatogenic compartments of the Klinefelter testis is needed to formulate a rational approach to fertility optimization and preservation in these men.
Important medical conditions associated with Klinefelter syndrome (KS) are categorized as: 1) motor, cognitive, and behavioral dysfunction; 2) tumors; 3) vascular disease; and 4) endocrine/metabolic and autoimmune diseases. Earlier diagnosis of KS may lead to earlier intervention with effective treatment.
We performed a literature review of the genetic etiology of Klinefelter syndrome, its effect on spermatogenesis, and the health of children born from men with Klinefelter syndrome following assisted reproductive technology.
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