Men's body mass index was not associated with clinical outcomes among couples undergoing conventional IVF, but male obesity was related to lower odds of live birth after intracytoplasmic sperm injection.
Male partners of couples with idiopathic recurrent spontaneous miscarriages with no significant changes in the basic semen parameters reveal significant methylation aberration in spermatozoa at the H19 ICR.
This work evaluates the GP6 gene polymorphism in 27 patients with sticky platelet syndrome and fetal loss and in 42 healthy control subjects. Higher occurrence of two haplotypes in the patients shows that GP6 gene polymorphism may be associated with platelet hyperaggregability.
Immature germinal vesicle oocytes recovered from stimulated cycles were spontaneously matured in vitro. Using real-time technology, the dynamics of nuclear maturation were studied and the most favorable duration of MII arrest (i.e., that corresponding with the highest number of matured oocytes displaying a normal activation response) was determined.
Raman microspectroscopy was able to identify oxidative sperm nDNA damage. The differences in spectral profiles were corroborated by Fourier transform infrared spectroscopy, and the levels of fragmentation were consistent with flow-cytometric assessment.
The relationships between primordial follicles, follicular recruitment, and circulating AMH are dynamic, reflecting the different stages of the reproductive lifespan. This article discusses these relationships and their clinical implications.
Correctly diagnosing miscarriage is a fundamental decision. Systematic review of the evidence suggests criteria to determine early pregnancy viability are flawed and may lead to inadvertent termination. Recent publications suggest more conservative guidance is needed.
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