Because nerve fibers present in endometriosis play an important role in pain mechanisms, antiangiogenic treatment that decreases nerve fibers provides a novel therapeutic approach.

The expression of E receptors as well as GREB1, Cyclin D1, and c-myc is increased in peritoneal endometriotic lesions compared with control eutopic endometrium.

Men's body mass index was not associated with clinical outcomes among couples undergoing conventional IVF, but male obesity was related to lower odds of live birth after intracytoplasmic sperm injection.

Male partners of couples with idiopathic recurrent spontaneous miscarriages with no significant changes in the basic semen parameters reveal significant methylation aberration in spermatozoa at the H19 ICR.

Defining the molecular and cellular mechanisms of Chlamydia-induced tubal transport and progression of tubal implantation will be a key question for future studies.

This work evaluates the GP6 gene polymorphism in 27 patients with sticky platelet syndrome and fetal loss and in 42 healthy control subjects. Higher occurrence of two haplotypes in the patients shows that GP6 gene polymorphism may be associated with platelet hyperaggregability.

Frozen-embryo transfer in substituted cycles resulted in higher pregnancy rates but also increased pregnancy loss, leading to similar clinical pregnancy and delivery rates for the protocols studied.

We aim to investigate the metabolomic signature of trisomy 21 human embryos, suggesting that differential metabolomic markers found in spent media could be used for chromosomal embryo selection.

Female age and blastocyst expansion are associated with live birth in patients undergoing SET. Many other clinical factors including obesity do not appear to affect SET outcome.

Immature germinal vesicle oocytes recovered from stimulated cycles were spontaneously matured in vitro. Using real-time technology, the dynamics of nuclear maturation were studied and the most favorable duration of MII arrest (i.e., that corresponding with the highest number of matured oocytes displaying a normal activation response) was determined.

The delivery rate achieved after the vitrification of early cleavage- and blastocyst-stage embryos is not affected by the embryo developmental stage or any other variable related to the warming cycle.

Older men with higher dietary and supplement intake of certain micronutrients, including vitamin C, vitamin E, folate, and zinc, but not b-carotene, may produce sperm with less DNA damage.

Raman microspectroscopy was able to identify oxidative sperm nDNA damage. The differences in spectral profiles were corroborated by Fourier transform infrared spectroscopy, and the levels of fragmentation were consistent with flow-cytometric assessment.

Reflections on "Oxidative DNA damage in human sperm can be detected by Raman microspectroscopy" by Sanchez et al.

Reflections on "Fertility preservation utilizing controlled ovarian hyper-stimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome" by Reichman et al.

Reflections on "Fertility following tubal ectopic pregnancy: results of a population-based study" by De Bennetot et al.

The purpose of this ASRM and SREI Practice Committee Opinion is to address controversies regarding the diagnosis and potential treatment of luteal inadequacy.

This ASRM Practice Committee document defines recurrent pregnancy loss and reviews possible causes and diagnostic strategies.

The relationships between primordial follicles, follicular recruitment, and circulating AMH are dynamic, reflecting the different stages of the reproductive lifespan. This article discusses these relationships and their clinical implications.

Correctly diagnosing miscarriage is a fundamental decision. Systematic review of the evidence suggests criteria to determine early pregnancy viability are flawed and may lead to inadvertent termination. Recent publications suggest more conservative guidance is needed.