To our knowledge, this is the first case report describing a cardiac-extending IV leiomyomatosis successfully extracted from the gonadal vein without sternotomy.

Considering the greater ovarian cortical thickness at the mesial side, this incision could provide better identification of the cleavage plane, reducing cyst rupture risk and also sparing ovarian residual function.

The high prevalence of diabetes in Klinefelter patients is possibly due to abnormal karyotypes. Other risk factors, such as low T and high triglyceride, may also contribute to the development of diabetes.

Circulating AMH declined significantly after gonadal suppression with long-acting GnRH agonist, and AMH recovered to pretreatment levels after discontinuation of GnRH agonist. This is an indication of partial gonadotropin-dependence of AMH.

In studying the association of adrenal and ovarian androgens with metabolic parameters in women with polycystic ovary syndrome, distinguishing between adrenal and ovarian hyperandrogenism is important to evaluate metabolic risk.

Peritubular cell secreted factor(s) may modulate T production by Leydig cells in a nonclassic mode, independent of StAR gene expression even in a gonadotropin-deficient environment.

Gonadotropin-releasing hormone analogues leuprolide acetate and cetrorelix acetate directly regulate extracellular matrix components COL1A1, fibronectin, and versican in human uterine leiomyoma cells relative to patient-matched myometrial cells.

Two vitrification protocols were shown to preserve the morphology and viability of human preantral follicles. After warming and xenografting to nude mice for 1 week, these follicles were able to survive and develop.

We describe the existence of a specific postnatal window of vulnerability during which estradiol valerate exposure irreversibly programs changes in the follicular development, ovulation, and cyclic estrual activity of rats.

The IVF facilities providing PGD services expose themselves to liability for misdiagnosis. Conducting the procedure in a competent manner and providing proper informed consent may deter litigation.

General population study of spontaneous fertility after ectopic pregnancy, according to the treatment. Conservative strategy should be favored, especially for patients with risk factors of infertility.

Gonadotropin-releasing hormone agonist cotreatment in conjunction with conditioning chemotherapy before stem cell transplantation may significantly decrease gonadotoxicity and premature ovarian failure in lymphoma but not in leukemia patients.

Tumor necrosis factor-a gene mutations may be responsible for the genetic susceptibility of Korean women to idiopathic primary ovarian insufficiency.

The rate of change of AMH is an independent predictor of TTM in late reproductive-age women and increased precision of estimates of TTM when included with baseline AMH levels and age.

Hypoestrogenic intervals at the beginning of the menstrual cycle in a population-based sample decrease and then increase in length with age, potentially reflecting both follicular depletion and hyperstimulation.

Proximity frequencies of autosomic bivalents to the XY pair in metaphase I human spermatocytes were evaluated, showing a nonrandom bivalent distribution and a relative position pattern notably preserved from pachytene to metaphase I.

Blastocyst PGD of mutation load and gender was applied for the first time. Results demonstrate that the trophectoderm is predictive of inner cell mass and newborn mutation loads and that simultaneous gender selection can be used to reduce the transgenerational risk of inheritance.

Analyzing 489 patients who were 40 years of age or younger with grade 1 intramucous endometrial adenocarcinoma, uterine and ovarian preservation was not associated with an increase in cancer-related mortality.

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Interleukin (IL)-17A was present in neutrophils in endometrioma and it increased Gro-a secretion from endometrioma stromal cells, which induced neutrophil migration. IL-17A in neutrophils may contribute to the development of endometriosis.

Because nerve fibers present in endometriosis play an important role in pain mechanisms, antiangiogenic treatment that decreases nerve fibers provides a novel therapeutic approach.

The expression of E receptors as well as GREB1, Cyclin D1, and c-myc is increased in peritoneal endometriotic lesions compared with control eutopic endometrium.

Men's body mass index was not associated with clinical outcomes among couples undergoing conventional IVF, but male obesity was related to lower odds of live birth after intracytoplasmic sperm injection.

Male partners of couples with idiopathic recurrent spontaneous miscarriages with no significant changes in the basic semen parameters reveal significant methylation aberration in spermatozoa at the H19 ICR.

Defining the molecular and cellular mechanisms of Chlamydia-induced tubal transport and progression of tubal implantation will be a key question for future studies.

This work evaluates the GP6 gene polymorphism in 27 patients with sticky platelet syndrome and fetal loss and in 42 healthy control subjects. Higher occurrence of two haplotypes in the patients shows that GP6 gene polymorphism may be associated with platelet hyperaggregability.

Frozen-embryo transfer in substituted cycles resulted in higher pregnancy rates but also increased pregnancy loss, leading to similar clinical pregnancy and delivery rates for the protocols studied.

We aim to investigate the metabolomic signature of trisomy 21 human embryos, suggesting that differential metabolomic markers found in spent media could be used for chromosomal embryo selection.

Female age and blastocyst expansion are associated with live birth in patients undergoing SET. Many other clinical factors including obesity do not appear to affect SET outcome.

Immature germinal vesicle oocytes recovered from stimulated cycles were spontaneously matured in vitro. Using real-time technology, the dynamics of nuclear maturation were studied and the most favorable duration of MII arrest (i.e., that corresponding with the highest number of matured oocytes displaying a normal activation response) was determined.

The delivery rate achieved after the vitrification of early cleavage- and blastocyst-stage embryos is not affected by the embryo developmental stage or any other variable related to the warming cycle.

Older men with higher dietary and supplement intake of certain micronutrients, including vitamin C, vitamin E, folate, and zinc, but not b-carotene, may produce sperm with less DNA damage.

Raman microspectroscopy was able to identify oxidative sperm nDNA damage. The differences in spectral profiles were corroborated by Fourier transform infrared spectroscopy, and the levels of fragmentation were consistent with flow-cytometric assessment.

Reflections on "Oxidative DNA damage in human sperm can be detected by Raman microspectroscopy" by Sanchez et al.

Reflections on "Fertility preservation utilizing controlled ovarian hyper-stimulation and oocyte cryopreservation in a premenarcheal female with myelodysplastic syndrome" by Reichman et al.

Reflections on "Fertility following tubal ectopic pregnancy: results of a population-based study" by De Bennetot et al.

The purpose of this ASRM and SREI Practice Committee Opinion is to address controversies regarding the diagnosis and potential treatment of luteal inadequacy.

This ASRM Practice Committee document defines recurrent pregnancy loss and reviews possible causes and diagnostic strategies.

The relationships between primordial follicles, follicular recruitment, and circulating AMH are dynamic, reflecting the different stages of the reproductive lifespan. This article discusses these relationships and their clinical implications.

Correctly diagnosing miscarriage is a fundamental decision. Systematic review of the evidence suggests criteria to determine early pregnancy viability are flawed and may lead to inadvertent termination. Recent publications suggest more conservative guidance is needed.