During sympathetic stimulation with a mental stress test, young patients with the classic PCOS phenotype showed lower heart rate variability response versus a healthy control group, after adjustment for age.
The high plasma testosterone levels in swimmers did not have a detectable effect on bone mass acquisition. Among various factors, menstrual disorders may reduce the potentially favorable effect of androgens on bone.
The levels of follicular fluid and serum hepatocyte growth factor (HGF) and the expression of c-Met in polycystic ovary syndrome were determined along with the importance of HGF/c-Met signaling in fertilization success.
G-protein-coupled estrogen receptor-30 (GPR30) is highly expressed in uterine leiomyoma tissue and localized in the nuclei of leiomyoma cells; 17b-estradiol increases GPR30 expression in cultured leiomyoma smooth muscle cells.
Oxytocin receptor (OTR) levels in myometrial cells correlate with the severity of dysmenorrhea and uterine contractility in women with adenomyosis, and both trichostatin A and andrographolide dose-dependently inhibit OTR expression.
Cigarette smoking is not associated with quantitative differences in ciliation or ciliogenesis factor expression in human oviducts, suggesting other pathophysiologic mechanisms underlie the increased risk of ectopic pregnancy in women who smoke.
A scoring system aid in triage of women at risk for ectopic pregnancy validated in a racially, geographically diverse cohort, with comparable test characteristics for viable intrauterine and nonviable pregnancies.
Aberrant expression of proinflammatory, anti-inflammatory, and angiogenic cytokines alters the endometrial milieu, affecting the endometrial development and receptivity during implantation window in women with idiopathic recurrent spontaneous miscarriage.
The performance of twin pregnancies after fetal reduction procedure was tested in a prospective cohort study. Our work supports a lack of causative relationship between fetal reduction and pregnancy endpoint.