Pituitary origin of persistently elevated human chorionic gonadotropin in a patient with gonadal failure
Pituitary Origin of Persistently Elevated Human Chorionic Gonadotropin in a Patient with Gonadal Failure
January 2013
All the papers from the January 2013 issue of Fertility and Sterility.
Cardiac autonomic modulation in polycystic ovary syndrome Does the phenotype matter
During sympathetic stimulation with a mental stress test, young patients with the classic PCOS phenotype showed lower heart rate variability response versus a healthy control group, after adjustment for age.
Relationships between the luteinizing hormone surge and other characteristics of the menstrual cycle in normally ovulating
Only 48% of LH surges in ovulating women are single peaks of <5 days. The variants are associated with significant differences in follicle size and hormone levels.
Testosterone secretion in elite adolescent swimmers does not modify bone mass acquisition: a 1-year follow-up study
The high plasma testosterone levels in swimmers did not have a detectable effect on bone mass acquisition. Among various factors, menstrual disorders may reduce the potentially favorable effect of androgens on bone.
The levels of hepatocyte growth factor in serum and follicular fluid and the expression of c-Met in granulosa cells in patients with polycystic ovary syndrome
The levels of follicular fluid and serum hepatocyte growth factor (HGF) and the expression of c-Met in polycystic ovary syndrome were determined along with the importance of HGF/c-Met signaling in fertilization success.
Differential expression of G protein coupled estrogen receptor 30 in human myometrial and uterine leiomyoma smooth muscle
G-protein-coupled estrogen receptor-30 (GPR30) is highly expressed in uterine leiomyoma tissue and localized in the nuclei of leiomyoma cells; 17b-estradiol increases GPR30 expression in cultured leiomyoma smooth muscle cells.
Progestin induced heart and neural crest derivatives expressed transcript 2 is associated with fibulin 1 expression in human endometrial stromal cells
Progestin-induced heart and neural crest derivatives expressed transcript 2 contributes to fibulin-1 expression in human endometrial stromal cells.
Allotransplantation of cryopreserved prepubertal mouse ovaries restored puberty and fertility without affection methylation profile of Snrpn DMR
Vitrification of prepubertal mouse ovaries did not affect the methylation profile of Snrpn-DMR or their development and fertility potential.
Dysmenorrhea and its severity are associated with increased uterine contractility and overexpression of oxytocin receptor (OTR) in women with symptomatic adenomyosis
Oxytocin receptor (OTR) levels in myometrial cells correlate with the severity of dysmenorrhea and uterine contractility in women with adenomyosis, and both trichostatin A and andrographolide dose-dependently inhibit OTR expression.
Live birth after orthotopic grafting of autologous cryopreserved ovarian tissue and spontaneous conception in Italy
A live birth was obtained after frozen/thawed ovarian tissue autologous transplantation in a patient with precocious ovarian failure after chemotherapy and bone marrow transplantation.
Interleukin 19 and Interleukin 22 serum levels are decreased in ovarian endometrioma
Serum interleukin-19 and -22 are decreased in ovarian endometrioma. They may be involved in the pathogenesis of endometriosis.
Attractiveness of women with rectovaginal endometriosis: a case-control study
Women with rectovaginal endometriosis were judged more physically attractive than women with peritoneal or ovarian endometriosis and than women with other benign gynecological conditions.
Pregnancy in dark winters Implications for fetal bone growth
The high prevalence of maternal hypovitaminosis D in women who are pregnant during winter months in northern latitudes may have detrimental effects on fetal skeletal growth.
Effect of cigarette smoking on human oviductal ciliation and ciliogenesis
Cigarette smoking is not associated with quantitative differences in ciliation or ciliogenesis factor expression in human oviducts, suggesting other pathophysiologic mechanisms underlie the increased risk of ectopic pregnancy in women who smoke.
Validation of a clinical risk scoring system based solely on clinical presentation for the management of pregnancy of unknown location
A scoring system aid in triage of women at risk for ectopic pregnancy validated in a racially, geographically diverse cohort, with comparable test characteristics for viable intrauterine and nonviable pregnancies.
Number and sequence of preceding miscarriages and maternal age for the prediction of Antiphospholipid Syndrome in women with recurrent miscarriage
The risk for antiphospholipid syndrome is the same after two, not necessarily consecutive, miscarriages, as for women with three or more miscarriages.
Proinflammatory cytokines induced altered expression of cyclooxygenase-2 gene results in unreceptive endometrium in women with idiopathic recurrent spontaneous miscarriage
Aberrant expression of proinflammatory, anti-inflammatory, and angiogenic cytokines alters the endometrial milieu, affecting the endometrial development and receptivity during implantation window in women with idiopathic recurrent spontaneous miscarriage.
Endometrin as Luteal Phase Support in Assisted Reproduction
Endometrin monotherapy provided comparable pregnancy rates (PRs) in fresh autologous and fresh donor oocyte cycles. The addition of P in oil to Endometrin improved PRs in frozen transfer cycles.
Elective cryopreservation of all embryos with subsequent cryothaw embryo transfer in patients at risk for ovarian hyperstimulation syndrome reduces the risk of adverse obstetric outcomes A preliminary study
Interval transfer of cryopreserved embryos derived from prior in vitro fertilization stimulation with elevated peak estradiol level reduces the risk of adverse obstetric outcomes.
Reduced versus nonreduced twin pregnancies Obstetric performance in a cohort of interventional conceptions
The performance of twin pregnancies after fetal reduction procedure was tested in a prospective cohort study. Our work supports a lack of causative relationship between fetal reduction and pregnancy endpoint.
Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles a systematic review and meta-analysis
In vitro fertilization outcomes may be improved by performing frozen instead of fresh embryo transfer. These results could be explained by avoiding the deleterious effects of controlled ovarian hyperstimulation on endometrial receptivity.
A common Asn680Ser polymorphism in the follicle stimulating hormone receptor gene is not associated with ovarian response to gonadotrophin stimulation in patients undergoing IVF
No association was demonstrated between follicle-stimulating hormone receptor gene variants and ovarian response in women undergoing in vitro fertilization treatment, but clinically relevant differences cannot be ruled out.
Clomiphene citrate potentiates the adverse effects of estrogen on rat testis and down regulates the expression of steroidogenic enzyme genes
The effects of clomiphene citrate on testicular function and steroidogenic enzyme gene expression were investigated in rats estrogenized with estradiol-3-benzoate.
Serum INSL3 is highly correlated with intratesticular testosterone in normal men with acute, experimental gonadotropin deficiency stimulated with low dose hCG A randomized controlled trial
Serum INSL3 correlates with intratesticular testosterone during hCG administration. Measurement of serum INSL3 may be a useful biomarker of intratesticular testosterone during hCG treatment of infertile men.
Association prevalence and clearance of human papillomavirus and antisperm antibodies in infected semen samples from infertile patients
This clinical study demonstrates the significant association between HPV sperm infection and ASAs and their clearance time in infertile patients.
Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury
This study provides the first evidence that inflammasome proteins are present in human 24 semen, and suggests that the inflammatory innate immune response contributes to 25 abnormal semen quality in SCI men.
Variance in total levels of phospholipase C zeta PLCζ in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability
Examination of total levels and localisation patterns of PLCζ in control and patient sperm. Sperm from control and OAD males exhibited significant variance in total levels and localization patterns of PLCζ protein.
Perfringolysin O as a useful tool to study human sperm physiology
Perfringolysin O selectively permeabilizes the plasma membrane of human spermatozoa and can be used to assess changes in the amount and distribution of the active cholesterol fraction present in this membrane.
Proteomic analysis of seminal plasma in adolescents with and without varicocele
Normal semen analysis may not reflect important alterations in protein levels in the seminal plasma. A classic proteomics approach shows that unbalanced apoptosis may prevent normal spermatogenesis in the adolescent varicocele.
Defective protein kinase A and C pathways are common causes of disordered zona pellucida ZP induced acrosome reaction in normozoospermic infertile men with normal sperm-ZP binding
Defective protein kinase A and C pathways are commonly associated with disordered ZP–induced acrosome reaction in normozoospermic infertile men with normal sperm-ZP binding.
Phospholipase C zeta rescues failed oocyte activation in a prototype of male factor infertility
Oocytes expressing mutant sperm phospholipase Cz (PLCz) fail to activate, but microinjection of wild-type human PLCz rescues failed activation and triggers embryo development.
G-protein β3 Subunit Gene 825C T Polymorphism and its Association with the Presence Severity and Duration of Vasculogenic Erectile Dysfunction
The CT genotype of GNB3 gene was more prevalent in patients with erectile dysfunction. The interaction between the T allele and erectile dysfunction was significant (P¼.004).
Modifiable Aspects of IVF to Reduce Perinatal Morbidity
Reflections on “Elective cryopreservation of all embryos with subsequent cryothaw embryo transfer in patients at risk for ovarian hyperstimulation syndrome reduces the risk of adverse obstetric outcomes: a preliminary study” by Imudia et al.
The Significance of insulin-like factor 3 as a marker of intratesticular testosterone
Reflections on “Serum insulin-like factor 3 is highly correlated with intratesticular testosterone in normal men with acute, experimental gonadotropin deficiency stimulated with low-dose human chorionic gonadotropin: a randomized, controlled trial” by Roth et al.
What proteomic analysis of semen can tell us
Reflections on Zylbersztejn DS et al. “Proteomic analysis of seminal plasma in adolescents with and without varicocele”
Definitions of infertility and recurrent pregnancy loss A committee opinion
This document contains the definitions for infertility and recurrent pregnancy loss as defined by the Practice Committee of the American Society for Reproductive Medicine.
Recommendations for gamete and embryo donation A committee opinion
This document provides the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors.
Criteria for number of embryos to transfer A committee opinion
Criteria for number of embryos to transfer A committee opinion
Mature oocyte cryopreservation: a guideline
Evidence indicates that vitrification and warming of unfertilized oocytes followed by fertilization, commonly by intracytoplasmic sperm injection (ICSI), result in subsequent pregnancy rates which are acceptable and this technique should no longer be considered experimental.
Role of increased male age in IVF and egg donation Is sperm DNA fragmentation responsible
A review of potential risks to offspring as well as the impact on fertility of advancing male age and a discussion of mechanisms by which male age may impact sperm.