Reflections on “Overweight men with nonobstructive azoospermia have worse pregnancy outcomes following microdissection testicular sperm extraction” by Ramasamy et al.

This document provides strategies, based on scientific principles and clinical experience, to reduce the risk of viral transmission in couples seeking treatment for infertility using their own gametes.

Prior to undergoing infertility treatments, vaccination guidelines should be reviewed and updated for all female patients.

The absence of scientific evidence for a beneficial effect of adjuvant androgens in poor responders is likely related to the lack of accurate assessment of theca cell function.

The adjusted risk of congenital anomalies in assisted reproductive technology versus spontaneously conceived children is only slightly increased, and it seems that malformation rates are declining over time.

Despite remaining data gaps, findings do not support that children conceived by ART differ in growth compared with non-ART children, although a signal of increased blood pressure warrants further investigation.

Recent evidence suggests that the initial association of adverse neurodevelopmental outcomes in children born after IVF was overstated.

We review the potential association between different components of ART and infertility with LBW, while acknowledging the limitations to interpretation of the existing literature.

Despite lack of the perfect study, the perinatal consequences of ART are apparent while investigation into long-term clinical outcome is needed and continues.