Children conceived by ART had higher mean total difficulties scores than planned, naturally conceived children, yet scores mostly remained within the “normal” range, and there was no significant increase in clinically relevant behavioral problems.
An analysis of 25,777 singleton full-term births after assisted reproduction showed that extended embryo culturing and frozen-thawed embryo transfer increased birth weight and that ovarian stimulation is a risk factor for low birth weight in fresh embryo transfer cycles.
Pregnancy showed a cMP increase. Differences in numbering and types of cMP in normal pregnancy, RM and PE have been demonstrated. Endothelial-derived cMP are increased in patients with antiphospholipid antibodies.
This study highlights the risk involving various genotypes and alleles of the interleukin (IL) 4 (C590T), IL-6 (G174C), IL-10 (1082A/G and 819C/T), and interferon-g (+874 A/T) polymorphism with recurrent miscarriage.
Human decidual natural killer (dNK) cells were cocultured with Toxoplasma gondii in vitro. Changes in dNK cell activities likely contribute to abnormal pregnancy outcomes due to infection with T. gondii.
Although pregnancy rates in “Bologna-criteria poor ovarian responders” treated with corifollitropin alpha in a GnRH antagonist protocol are low, this should be interpreted with caution given the very poor prognosis of this population.
In this follow-up study of a randomized controlled trial on preimplantation genetic screening (PGS), the percentage of 2-year-old children with one or more major abnormality in the group born after in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) with PGS did not exceed the percentage in those born after IVF/ICSI without PGS.
We developed a microfluidic device that can reduce the treatment time of intracytoplasmic sperm injection and compared the treatment time for porcine sperm injection using the method employing this device and the conventional microdroplet method.
Multiple-gestation pregnancies are the most significant morbidity after IVF, yet national data reports outcomes as per cycle pregnancy rates. This study provides estimates of the cumulative incidence of liveborn multiples and reports a low cumulative incidence of liveborn multiples, especially triplets.
This retrospective study analyzed the risk factors for development of significant liver dysfunction in pregnancy and it’s specific etiologies. Assisted reproduction was significantly associated with liver test abnormalities.
Overweight men have lower clinical pregnancy rate after microdissection testicular sperm extraction and intracytoplasmic sperm injection compared with men with normal weight. Men with body mass index >43 kg/m2 did not contribute to any pregnancies despite successful sperm retrieval.
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