Adrenocortical responses before and after bilateral oophorectomy suggest that ovarian factors have a limited role in the etiology of adrenal androgen excess of polycystic ovary syndrome.
All the papers from the February 2013 issue of Fertility and Sterility.
A double-blind, randomized, placebo-controlled trial on the effects of metformin on serum levels of 8-hydroxy-20-deoxyguanosine (8-OHdG) in women with polycystic ovary syndrome showed levels were statistically significantly reduced versus placebo.
Subclinical hypothyroidism in young women with polycystic ovary syndrome An analysis of clinical hormonal and metabolic parameters
Young women with polycystic ovary syndrome and subclinical hypothyroidism present higher serum levels of low-density lipoprotein cholesterol with no changes in other lipid profile parameters, insulin resistance, or phenotypic manifestations.
Down regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia while up regulation of the channel by Sheng Jing San treatment improves…
In rats with cyclophosphamide-induced asthenozoospermia, CatSper1 and sperm motility were significantly reduced, whereas Sheng-Jing-San treatment restored the cyclophosphamide-induced down-regulation of CatSper1 and improved the sperm motility.
Altered insulin induced relaxation of aortic rings in a dihydrotestosterone induced rodent model of polycystic ovary syndrome
Insulin-dependent vasorelaxation in aortic rings in a PCOS rat model is decreased (both NO-dependent or independent), and vitamin D treatment can improve only the NO-independent model.
Global metabolomic and amino acid profiles of spent culture media samples from embryos derived from either fresh or vitrified oocytes showed no statistically significant differences.
Quantification of nucleolar channel systems Uniform presence throughout the upper endometrial cavity
Nucleolar channel systems appear uniformly throughout the upper endometrial cavity, excluding the lower uterine segment, and preferentially in the functional luminal layers of the endometrium, indicating uniform secretory transformation.
Data presented here reveal the importance of evaluating the complete lipid profile, especially at early stages of life after the prenatal hyperandrogenism condition.
Dietary Fish Oil Supplementation Inhibits Formation of Endometriosis-Associated Adhesions in a Chimeric Mouse Model
In an established model of spontaneous adhesive disease associatedwith experimental human endometriosis in nude mice, development of adhesions was significantly reduced in animals provided with an antiinflammatory diet containing fish oil.
Leukemia inhibitory factor increases the invasiveness of trophoblastic cells through integrated increase in the expression of adhesion molecules and pappalysin 1 with a concomitant decrease…
Microarray data revealed altered expression of several novel invasion-associated molecules in leukemia inhibitory factor (LIF)-treated HTR-8/SVneo cells, wherein silencing of pappalysin 1 reduced LIF-mediated invasion.
Peripheral blood stem cell transplants did not result in endometrial engraftment in human and non-human primate models.
The study demonstrated that a specific survivin mRNA and protein are expressed in human oocytes and embryos. Embryos secrete survivin into culture media, and survivin concentrations are positively correlated with embryo cleavage rates.
The Accuracy and Reproducibility of the Endometrial Receptivity Array Is Superior to Histology as a Diagnostic Method for Endometrial Receptivity
In the same set of endometrial biopsies, the accuracy of the endometrial receptivity array diagnostic tool was superior to dating by endometrial histology, and was reproducible in the same patients 29–40 months later.
Knowledge about factors that influence fertility among Australians of reproductive age A population based survey
There are considerable knowledge gaps among Australians of reproductive age about the impact on fertility of age, weight, smoking, and timing of sex.
Effective anatomical and functional status of the lower uterine segment at term Estimating the risk of uterine dehiscence by ultrasound
Sonographic lower uterine segment evaluation may be a good noninvasive, repeatable, safe technique for defining profile risk of uterine dehiscence or worse in women with previous cesarean section, especially more than 18 months later.
The level of plasma soluble E-cadherin was elevated in patients with pelvic inflammatory disease as compared with that in normal controls and in the same patients after they received treatment.
In a primary ovarian insufficiency group, we identified one mutation and a frequent variant of the NR5A1/SF-1 gene. This work confirms the important role of steroidogenic factor 1 in ovarian function.
Pretreatment antimullerian hormone levels determine rate of posttherapy ovarian reserve recovery Acute changes in ovarian reserve during and after chemotherapy
Young women undergoing chemotherapy experience acute changes in ovarian reserve that recover in the months after therapy is completed. The rate of recovery of AMH is impacted by pretreatment levels.
We report the first-year results of the longest-lived human uterus allograft.
In cryopreserved semen from men with newly diagnosed cancer, all specimens show severe decline in postthaw total motile sperm count, with most severe reductions in the myeloid leukemia group.