Blastocyst embryo transfer improves the live-birth rate in good prognosis patients compared with cleavage-stage transfer. In unselected or poor prognosis patients, it is not proven superior to cleavage-stage transfer.
Suppression of aromatase cytochrome P450 may inhibit the in vivo growth of endometriosis lesions in baboons.
We discuss how the Affordable Care Act may impact fertility care.
Are imprinting disorders more prevalent after human in vitro fertilization or intracytoplasmic sperm injection?
There is solid evidence that Beckwith-Wiedemann syndrome is significantly positively associated with IVF or ICSI. There is no proof for a causal relationship between imprinted diseases and ART.
Epigenetic disturbances in in vitro cultured gametes and embryos: implications for human assisted reproduction
Despite accumulating evidence in animal models that in vitro culture of oocytes and embryos can interfere with epigenetic genome reprogramming, little is known about the epigenetic risks of human assisted reproductive technologies.
Epigenetic mechanisms maintain mitotically heritable differences in gene expression potential without altering the primary DNA sequence. This review highlights epigenetic mechanisms that are relevant to normal and abnormal human developmental and differentiation processes.
A review of epigenetics and ART.