The present study demonstrated that in PCOS neonates, the oxidative stress status was similar to that of GDM neonates and strongly associated with their mothers’ oxidative status.

This study is a cross-sectional analysis to determine the prevalence of PCOS in patients with psoriasis. The prevalence of PCOS in women with psoriasis is about 47%.

Ex vivo expanded myoma cells or transformed and immortalized by SV40ER lose in vivo tumorigenicity. Injections of uncultured primary myoma cells produce stable xenografts with unique similarity to human fibroids.

Ghrelin signaling is involved in the reproductive phenotype of ob/ob mouse.

Immature myeloid cells derived from placentas and tumors show similar molecular signatures. This common gene expression pattern may indicate that these cells share the same origins and functions.

Preovulatory gonadotropin stimulation induces changes in ovarian permeability, with an increase in the radii of the small and large pores and a threefold increase in the large pore fraction of the hydraulic conductance.

All human embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection are chromosomally abnormal and should be discarded for reproductive purposes.

Letrozole increases ovarian size and androgen production and upregulates Cyp17a1 messenger RNA expression in the rat ovary.

The expression of ACTL7a is up-regulated via the protein kinase A pathway and undergoes remodeling during the early period of capacitation in mouse spermatozoa.

Syndecan-1 inhibits invasiveness of epithelial endometriotic cells by modulating matrix metalloproteinases MMP-2 and MMP-9, plasminogen activator inhibitor-1, and interleukin-6 and is regulated by the microRNA miR-10b, both possible novel targets for therapeutic approaches.

In a rat model of allogeneic uterus transplantation, the immunosuppressant tacrolimus effectively prevented uterine rejection, and expression patterns of inflammation-/implantation-related proteins of the uteri were similar to those of controls.

Human blastocysts express microRNAs, many of which are important for embryonic and stem cell development. Differential expression of microRNAs based on ploidy and sex were discovered.

Embryos from outbred mice are sensitive to in vitro toxins and may provide a more reliable measure of quality for undefined culture components such as mineral oil.

An online questionnaire assessed fertility and ART knowledge of 599 childless men. These findings were compared to a sample of childless women. Significant knowledge gaps were identified.

In fertility care, we should listen to both members of the infertile couple. Our results show that experiences with patient-centered fertility care are only slightly different within the couple.

Cryopreserved donor oocytes are widely available from commercial “egg banks” (CEBs); with over 3,000 oocytes currently in storage and 600 pregnancies already conceived. Most CEBs use the vitrification cryopreservation technique.

CBX2 gene disruption, described in one case of 46,XY ovarian disorder of sex development (DSD), is not a common cause of other gonadal DSD forms.

Report describes two brothers with two homozygous PROKR2 missense changes and Kallmann syndrome, and their healthy heterozygous carrier parents.

Gene expression profiling at the human oocyte and blastocyst stage has identified similarities and differences in processes before and after embryonic genome activation.

Parents of boys with cancer want some sort of fertility preservation, even if the risks of infertility or the success rates in restoring fertility were 20%.

In utero exposures were not associated with a visualized endometriosis diagnosis in either an operative or population cohort of women in contrast to earlier evidence.

In the first experimental model of deep nodular endometriosis, lesions similar to endometriotic nodules were induced, and they invaded surrounding organs in more than 40% of cases.

In a Danish national register study on 523,757 women, an association between birth weight 4,500 g and an increased risk of PCOS in adult life was found in offspring of nondiabetic women.

African American women with fibroids have larger and more numerous fibroids compared with white women. Racial differences were not explained by a higher prevalence of known risk factors.

Children born to mothers who had more than two miscarriages, fertility problems, or prolonged time to pregnancy, had significantly higher risks of asthma during childhood. Maternal subfertility exposes offspring to an increased risk of asthma.

The kinase insert domain-containing receptor 604T/C polymorphism is associated with recurrent spontaneous abortion (RSA) in Korean women, whereas the 1719A/T polymorphism that is associated with RSA in Taiwanese Han women is not associated with RSA in Korean women.

This study identified a 12-gene signature in human cumulus cells predictive of pregnancy across multiple clinics. The positive predictive value of our test was 81% with an area under the receiver operating characteristic of 0.763  0.079.

With the use of time-lapse monitoring, to evaluate human embryo development, we describe a stage-dependent adverse response to atmospheric oxygen.

Neonatal and maternal outcomes were dramatically better for women undergoing two IVF singleton pregnancies compared with one IVF twin pregnancy.

Delayed administration of GnRH antagonist in a flexible protocol is associated with an attenuated pattern of ovarian response to stimulation but has no effect on implantation and pregnancy rates.

Testosterone therapy has a reversible suppression of spermatogenesis. Selective estrogen receptor modulators represent an alternative therapy for men who desire to maintain future potential fertility. Human chorionic gonadotropin therapy may be considered.

Density gradient and washing can remove HCV RNA or HIV RNA from microsurgical epididymal sperm aspiration or testicular sperm extraction samples obtained from HCV- or HIV-infected azoospermic men before ICSI.

Cationic surfactants show promise as womancontrolled spermicides. We show that, besides effects on vitality and motility, at lower concentrations they impair sperm function at various levels, not necessarily by acting as surfactants.

Asthenozoospermic spermatozoa exhibited a modification in plasma membrane rheology, and a reduced immunohistochemical expression of ezrin, Cdc42, CD9, F-actin, and b-tubulin, which could contribute to sperm functional impairment.

We discuss evidence that the null of GSTM1 and GSTM1-GSTM1 increased the risk of male factor infertility, but the null genotype of GSTT1 was not associated with an increased infertility risk.

Raman microspectroscopy scanning of single live sperm is able to distinguish the human zona pellucida–bound sperm from unbound sperm.

Reflections on “Uterine rejection after allogeneic uterus transplantation in the rat is effectively suppressed by tacrolimus” by Akhi et al.

Reflections on “Induction of endometriotic nodules in an experimental baboon model mimicking human deep nodular lesions” by Donnez et al.

Reflections on “The treatment of hypogonadism in men of reproductive age” by Kim et al.

This document describes the basics of sperm DNA integrity; assesses the evidence pertaining to the clinical utility of sperm DNA integrity testing; and targets areas that require more study.