Standardization of laparoscopic pelvic examination will make lesions in anatomically challenging locations less likely to miss.
Leptin is able to regulate the expression of different target enzymes throughout the P synthesis, such as P450scc and 3bHSD, in a dose-dependent manner.
Follicle microenvironment associated alterations in gene expression in the mouse oocyte and its polar body
Changes in the follicle microenvironment lead to quantifiable differences in gene expression in individual oocytes and their polar bodies.
Cell membrane proteins from oviductal epithelial cell line protect human spermatozoa from oxidative damage
Cell membrane proteins from an oviductal epithelial cell line have protective effects on spermatozoa against oxidative stress.
Kisspeptin stimulates progesterone secretion via the Erk1/2 mitogen-activated protein kinase signaling pathway in rat luteal cells
Kisspeptin could augment progesterone secretion via stimulating key steroidogenic enzymes and phosphorylate Erk1/2 mitogen-activated protein kinase in cultured luteal cells.
Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation
Dimethylsulfoxide may up-regulate AQP7 expression in mouse oocytes by both osmolarity-dependent and osmolarity-independent pathways, and up-regulation of AQP7 facilitates water diffusion in mouse oocytes.
Feedback to professionals on patient-centered fertility care is insufficient for improvement: a mixed-method study
In audit and feedback methods to improve patientcenteredness in fertility care, the key issues are increasing professionals’ knowledge about their performance and their desire to make changes.
Training in empathic skills improves the patient-physician relationship during the first consultation in a fertility clinic
Training in empathic skills for physicians resulted in higher self-reported patient satisfaction regarding information quality, communication skills, time dedicated, and expertise in patients from different countries accessing infertility treatment.
In vitro fertilization for Orthodox Jewish couples: antagonist cycle modifications allowing for mikveh attendance before oocyte retrieval
A novel modification of gonadotropin-releasing hormone antagonist IVF protocols for postponement of retrieval until at least 7 days after cessation of menstruation allows for observance of ritual Jewish practices.
Preimplantation genetic screening using fluorescence in situ hybridization in patients with repetitive implantation failure and advanced maternal age: two randomized trials
Preimplantation genetic screening using fluorescence in situ hybridization improves live-birth rates in patients with repetitive implantation failure or advanced maternal age.
Uterine rudiments in patients with Mayer-Rokitansky-Küster-Hauser syndrome consist of typical uterine tissue types with predominantly basalis-like endometrium
Immunohistochemical analysis reveals all uterine tissue types in uterine rudiments of patients with MRKH syndrome. Endometrial components show reduced proliferative capacity and basalis-like differentiation.
Self-reported menopausal symptoms, coronary artery calcification, and carotid intima-media thickness in recently menopausal women screened for the Kronos early estrogen prevention study (KEEPS)
In recently menopausal women, self-reported climacteric symptoms do not correlate with subclinical atherosclerosis.
Evaluation of targeted next-generation sequencing–based preimplantation genetic diagnosis of monogenic disease
A methodology of next-generation sequencing was developed for preimplantation genetic diagnosis and found to be highly consistent with two independent methods of single-gene disorder screening.
Preimplantation genetic diagnosis outcomes and meiotic segregation analysis of robertsonian translocation carriers
The rate of alternate embryos can be affected by the sex of the robertsonian translocation carrier, and aneuploidy of chromosome 18 was significantly (P<.001) increased in 3:0-segregated or chaotic embryos.
Human preantral follicles can be successfully cryopreserved before or after isolation without impairing their ability to survive and grow in vitro.
Optimizing human oocyte cryopreservation for fertility preservation patients: should we mature then freeze or freeze then mature
Germinal vesicle and metaphase I oocytes should be matured in vitro before cryopreservation to optimize the reproductive potential of all retrieved oocytes.
MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors
MicroRNA miR-145 inhibits proliferation, invasiveness, and the stem cell phenotype of endometriotic cells by targeting multiple cytoskeletal elements and pluripotency factors, emerging as a novel target for therapeutic approaches.
Dopamine receptor D2 genotype (3438) is associated with moderate/severe endometriosis in infertile women in Brazil
The frequency of the dopamine receptor D2 polymorphism 2 was increased in subjects with peritoneal moderate/severe endometriosis.
OCT4 is significantly up-regulated in human ectopic endometriotic tissues. The OCT4 expression may contribute to the pathology of ectopic endometrial growth by stimulating the migration of endometrial cells.
Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach
The prevalence of infertility in the United States was approximately twofold higher when estimated by a current duration approach vs. a traditional constructed measure (15.5% vs. 7.0%, respectively).