July 2013

All the papers from the July 2013 issue of Fertility and Sterility.

Is the fertile window extended in women with polycystic ovary syndrome? Utilizing the Society for Assisted Reproductive Technology registry to assess the impact of reproductive aging on live-birth rate

Below the age of 40, women with polycystic ovary syndrome have higher clinical pregnancy and live-birth rates after in vitro fertilization compared with women with tubal factor infertility. After 40, despite a higher oocyte yield, there is no difference in pregnancy outcomes.

Altered circulating levels of matrix metalloproteinases 2 and 9 and their inhibitors and effect of progesterone supplementation in women with endometriosis undergoing in vitro fertilization

Overexpression of matrix metalloproteinases (MMPs) 2 and 9 and decrease in tissue inhibitor of MMP (TIMP) 1 were associated with poor IVF outcome in women with endometriosis. Progesterone supplementation following IVF improved the MMP-9/TIMP-1 imbalance significantly in these women.