Peroxynitrite generated in inflammatory states disrupts the cumulus oocyte complex and the spindle apparatus by dispersing and compromising the viability of cumulus cells, which may lead to infertility.
Fallopian epithelial cells expressing FasL induce apoptosis of activated human T lymphocytes and endometrial cells, but endometrial cells derived from patients with endometriosis were resistant to the induction of apoptosis.
Increased transforming growth factor-b1 and decreased levels of its receptor, soluble endoglin are found in women with polycystic ovarian syndrome (PCOS) and may be implicated in PCOS pathogenesis and its increased risk for ovarian hyperstimulation.
After an educational intervention, university students in Australia had significantly increased knowledge of fertility and IVF effectiveness and significantly decreased desired ages at commencement and completion of childbearing.
The coital frequency of infertile couples was studied. Median monthly coitus was 7 and the lowest quartile was <5. Older age and erectile dysfunction were independent predictors of less frequent coitus in this population. Authors
We identified 25 serum proteins (4 down-regulated, 21 up-regulated) that were differentially expressed between adenomyosis patients and healthy women using iTRAQ labeling technology; 3 of these proteins were also analyzed using Western blotting.
Inverse associations were observed between serum bisphenol-A (BPA) concentration and androstenedione, free testosterone, and free androgen index and a positive association between serum BPA concentration and sex hormone-binding globulin.
Obesity was associated with PCOS in adolescents. Studies based on diagnosis codes only may underestimate the prevalence of PCOS and overestimate the magnitude of the association between obesity and PCOS.
Nasal epithelial adrenomedullin expression is decreased in tubal ectopic pregnancy, which is associated with reduced ciliary beat frequency, and this may help predict the risk of tubal ectopic pregnancy.
Long-acting reversible contraceptive use remains low among young women with little progress in the last decade, pointing to the failure of family planning policies in altering contraceptive norms in Franc
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