September 2013

All the papers from the September 2013 issue of Fertility and Sterility.

Is neonatal uterine bleeding involved in the pathogenesis of endometriosis as a source of stem cells?

Endometrial bleeding in the neonate, an event totally neglected by modern investigators, may play a role in the pathogenesis of at least early onset endometriosis and represent a potential source of endometrial stem cells. The bleeding is a well-established phenomenon occurring at the end of the first week, but is more often occult than visible. The structure and functional obstruction of the endocervical canal in the fetus at term suggest increased likelihood of retrograde flow of the endometrial shedding.

Polar body biopsy

Polar body biopsy combined with array comparative genomic hybridization allows detection of maternal chromosomal aberrations. Although it has limitations, it can be seen as an alternative to blastomere and trophectoderm biopsy.