October 2013

All the papers from the October 2013 issue of Fertility and Sterility.

Comparison of gene expression profiles in granulosa and cumulus cells after ovulation induction with either human chorionic gonadotropin or a gonadotropin releasing hormone agonist trigger

The follicle transcriptomes after human chorionic gonadatropin and gonadotropin-releasing hormone agonist triggering present significant differences. The top biofunctions represented by the differentially expressed genes were steroidogenesis and angiogenesis in cumulus and mural granulosa cells, respectively.

The national epidemic of multiple pregnancy and the contribution of assisted reproductive technology

Multiple pregnancy remains the most common complication of ART. The incidence of high-order multiple (HOM) pregnancies (triplets and greater) increased fivefold within 18 years and the total number peaked a decade ago. The incidence of twins and HOMs remains high but the proportion due to ART is much less than previously suspected, and the relative contribution of other factors greater.