In vitro maturation (IVM) of oocytes followed by a “freeze-all” embryo strategy results in promising clinical outcomes in patients with polycystic ovary syndrome and circumvents the potential problem of suboptimal endometrial quality in IVM cycles.
The follicle transcriptomes after human chorionic gonadatropin and gonadotropin-releasing hormone agonist triggering present significant differences. The top biofunctions represented by the differentially expressed genes were steroidogenesis and angiogenesis in cumulus and mural granulosa cells, respectively.
Human cadaver testes were infused with 99mtechnetium-labeled green fluorescent protein-positive testicular cells. This study shows that injecting a cell suspension in seminiferous tubules is possible, though further optimization is required.
Basic semen parameters are consistent through 34 years of age. Thereafter, ejaculate volume, sperm numbers, motility, proportions of sperm of normal morphology, and the ratio of Y- to X-bearing sperm decline.
Multiple pregnancy remains the most common complication of ART. The incidence of high-order multiple (HOM) pregnancies (triplets and greater) increased fivefold within 18 years and the total number peaked a decade ago. The incidence of twins and HOMs remains high but the proportion due to ART is much less than previously suspected, and the relative contribution of other factors greater.
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