The technique described in this video article may represent a step toward a more complete removal of endometriotic implants and better colorectal outcomes.

The abundant TNF-a in the peritoneal fluid of women with endometriosis plays an important role in endometriosis-induced embryotoxicity. The TNF-a inhibitors could potentially be used to treat endometriosis-related infertility.

Bone morphogenetic protein 4 increased oocyte formation from adult mouse ovary-derived oogonial stem cells via activation of Smad1/5/8 signaling and key meiosis commitment genes.

This study demonstrates for the first time a selective vascular disrupting effect of CA4P on endometriotic lesions, indicating that vascular disrupting agents may be suitable for the therapy of endometriosis.

Oogonial stem cells exhibited a gene expression profile partially overlapping with, but distinct from, other stem cells and germ cells, and they showed altered numbers during the reproductive cycle inversely related to meiotic commitment.

Growth differential factor-9 can inhibit the production of testosterone in mouse theca interstitial cells and suppress corresponding gene expression.

Fetal and fetal germ cell exposure to endometriosis in utero alters gene expression in first- and second-generation eight-cell embryos.

Oocytes have a vast repertoire of multidrug-resistant transporters. These protective effluxers change overall activity during maturation, and inhibition of these transporters increases cell susceptibility to toxicants.

Metoclopramide-induced hyperprolactinemia changed the amounts of murine uterine chondroitin, dermatan, and heparan sulfate during the estrous cycle.

The spatiotemporal expression and regulatory patterns of the tight junction protein Claudin-3 during embryo implantation using mouse and cell culture models.

Metformin administration in normally cycling women may decrease the production of CRH and UCN in endometrium during the midluteal phase of the menstrual cycle.

The levels of 2-methoxyestradiol are elevated in late luteal tissue and reduce the angiogenic vascular endothelial growth factor action in granulosa lutein cells.

We discuss health-related quality of life in patients with polycystic ovary syndrome. Mediating factors, especially psychological distress, self-esteem, body image and sexual function play an important role and should be taken into consideration and adequately treated if present.

Conventional IVF may be the preferred insemination method in the initial treatment of couples with unexplained infertility, but split IVF-ICSI becomes preferable if more than one IVF cycle is necessary.

Progesterone for luteal support after ovulation induction IUI was associated with increased likelihood of pregnancy and live birth in gonadotropin cycles but not in clomiphene citrate (CC) cycles.

Endometrial polyps in premenopausal women demonstrate a range of immunologic disturbances, including mast cell and regulatory T-cell infiltration. These likely contribute to symptoms of infertility and abnormal bleeding.

The first clinical pregnancy after uterus allotransplantation is presented.

After long-term xenotransplantation and exogenous stimulation, a high pool of quiescent follicles and follicular development up to the antral stage were evidenced in cryopreserved ovarian tissue from prepubertal patients.

Women electing oocyte cryopreservation know about age-related infertility yet continue to delay childbearing. Fertility preservation can increase a woman’s security regarding her reproductive future.

Continuous use of oral contraceptives after surgery is associated with a statistically significant reduction in dysmenorrhea, non-menstrual pelvic pain, and endometrioma recurrence.

Deep endometriosis may impair visceral and motor function owing to fibrotic neural involvement. Our pilot study seems to showthatdetrusor function could be significantly compromised, even in asymptomatic women.

The high prevalence of subclinical hypothyroidism among women with recurrent early pregnancy loss did not appear to impact the live-birth rates in this population.

M2/ANXA5 carriers show a trend of maximal recurrent pregnancy loss risk in the 10th to 15th week of gestation with a confirmed partner risk.

Among assisted conceptions, only nondonor in vitro fertilization/intracytoplasmic sperm injection singleton pregnancies need adjustments of the PAPP-A in first-trimester Down syndrome screening.

We studied the effect of single-dose systemic methotrexate treatment on ovarian reserve in ectopic pregnancy and concluded that methotrexate treatment has no effect on short-term ovarian reserve.

Data from 2,040 intracytoplasmic sperm injection patients combining embryo morphology with expression of sHLA-G (a noninvasive embryo marker) show improved pregnancy outcome and the theoretical potential to reduce multiple pregnancies.

Dual trigger with gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin improves implantation, clinical pregnancy, and live-birth rates for normal responders in GnRH-antagonist IVF-ICSI cycles.

Thin endometrium does not seem to influence oocyte donation outcome.

After analyzing the influence of different embryo culture media on the weight of the newborn, the results do not show any relationship between them.

We describe two distinct mechanisms of in vitro hatching related to fertilization method and demonstrate that hatching pattern is associated with fertilization method, but not with clinical pregnancy.

Poor, normal, and high ovarian responses were defined with the use of the ovarian sensitivity index, the ratio between oocyte yield and total dose of FSH, in a large unselected IVF cohort.

High numbers of diverse kinds of bacteria were present in the semen of both sperm donors and infertility patients. There were no significant differences between these two groups based on community composition.

Seminal CRISP1 was measured to distinguish between obstructive and nonobstructive azoospermia. The receiver operating characteristic plots demonstrated a high diagnostic accuracy for CRISP1 to diagnose the cause of azoospermia.

Sperm motility and normal morphology were higher in idiopathic anejaculation patients who collected their sperm by nocturnal emissions than in those who collected their sperm by penile vibratory stimulation or electroejaculation.

This study indicates methylation errors in oligozoospermia. We identified variants in DNMT3A and DNMT3L in men with altered methylation, but we did not find any association with DNA methylation defects and ART outcome.

Standard sperm evaluation, human papillomavirus (HPV) DNA detection, and in situ hybridization analysis were performed in 308 patients undergoing IVF procedures. Oncogenic HPV genotypes were detected on spermatozoa from asymptomatic subjects.

Reflections on “Vascular disrupting effects of combretastatin A4 phosphate on murine endometriotic lesions” by Feng et al.

Reflections on “Clinical pregnancy after uterus transplantation” by Akar et al.

Ethical considerations of preserving fertility after gonadotoxic treatment are discussed.

This document describes the responsibilities and strategies for fertility preservation in patients undergoing gonadotoxic medical therapy or radiation therapy or gonadectomy.